Compatibility and System Requirements

EndNote loves both the Windows® and Macintosh® platforms. Here’s how to check if your current systems and programs are EndNote-ready.



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Cross-Platform Compatibility



Windows compatibility and system requirements

What you need:

  • Windows 10
  • 1 gigahertz (GHz) or faster x86-bit or x64-bit processor
  • 600 MB hard disk space available
  • Minimum 2 GB of available RAM

Word processor software

  • Microsoft Word [CWYW] for Windows: 2010, 2013, 2016, 2019, Office 365 (locally installed desktop version only)
  • Apache OpenOffice [CWYW] for Windows: 3.x, 4.x
  • LibreOffice [CWYW] for Windows: 4.x, 5.x, 6.x (32-bit)
  • Partner CWYW Integration: Wolfram Mathematica 8

An Internet connection is required to register for online access, search online databases, find full text and automatically update references.

Macintosh compatibility and system requirements

What you need:

  • macOS 10.10 and above
  • Intel-based Macintosh
  • Hard disk with 700 MB available
  • Minimum 2GB of available RAM

Word processor software

  • Microsoft Word [CWYW] for macOS: 2016, 2019, Office 365 (locally installed desktop version only) 
  • Partner integration for Cite While You Write: Apple® Pages 
  • Partner CWYW Integration: Wolfram Mathematica 8 

EndNote online compatibility and requirements

Browser support for Web Application*

  • Microsoft Internet Explorer® 8.x or later
  • Firefox® 27 or later
  • Safari® 5.0 or later
  • Chrome® 31 or later

Browser support for Web Capture**

  • Add-on*
    • Microsoft Internet Explorer 8.x or later
  • Bookmarklet*
    • Microsoft Internet Explorer 8.x (32-bit) or later
    • Firefox 27 or later
    • Safari 5.0 or later
    • Chrome 31 or later

*Applies to both Macintosh and Windows browser versions, except for Internet Explorer, which is Windows only

**Cookies and JavaScript must be enabled

EndNote Click Browser Plugin

Supports the latest Chrome, Edge, Firefox, and Opera Browsers

Network compatibility and system requirements

EndNote libraries can be accessed on a network – including networks with Macintosh and Windows workstations. Multiple users on a network can access an EndNote library simultaneously in read-only mode. This allows users to search for references, cite them in their papers and create bibliographies. EndNote does not allow multiple users on a network to edit a single library at the same time.

Installation and deployment

On Windows networks, EndNote can be deployed with MSI installer technology using scripting or via Group Policy.


  • Windows Server 2003 & 2003 R2
  • Windows Server 2008 & 2008 R2
  • Windows Server 2012 & 2012 R2

If you have technical questions regarding the use of EndNote on a network, contact Support.


EndNote Cross-Platform Compatibility

What you need:

EndNote libraries are cross-platform compatible. Following the EndNote end user license agreement, this means: 

  • Individuals who purchase a single user license can install EndNote on up to three computers for their personal use.
  • Sharing a license with other users is not allowed under the individual license agreement.
  • Those computers can be any combination of Mac and Windows machines.
  • By creating or logging into an EndNote online account (under preferences > Sync), that individual can sync their library across all three computers, as well as access it through EndNote online and the iPad app. 

NOTE: Your EndNote product key is required for activation. Your key is the 25-character code you received at time of purchase. Can’t find your key? Contact Support.